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NASDAQ · ALNY · Biotechnology

Alnylam Pharmaceuticals, Inc. (ALNY) stock analysis

$225.10−2.43%Data as of Oct 21, 2026
  • ALNY lost 10.6% over the past month versus 0.0% for the S&P 500, ranking 87th of 100 Nasdaq 100 stocks.
  • Over 12 months it returned −54.2%, 70.0 points behind the S&P 500, and trades 53.3% below its 52-week high.
  • In the last 30 days 0 analysts raised earnings estimates and 2 cut; forward EPS moved 0.0% (−6.9% over 90 days).
  • It sits in the Biotech segment of the Healthcare Value Chain, where the 1-month median return is +0.4%.
  • The daily chart reads Intermediate downtrend · Decline (since Oct 7, 2026).
Market cap$30.1B
12-month return−54.2%
Forward P/E18.0×
Mean target vs price+64.2%

One-year price with 50- and 200-day averages

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228308388468JanAprJulOct
225.1050-day200-day

Performance vs the market

Total price return against the S&P 500 (SPY) and the median of US stocks in the same sector.

ALNY−10.6%
Sector median−8.7%
S&P 5000.0%
ALNY−16.2%
Sector median−5.4%
S&P 500+4.7%
ALNY−27.5%
Sector median−1.5%
S&P 500+8.7%
ALNY−54.2%
Sector median+1.7%
S&P 500+15.8%
1-month rank in the Nasdaq 10087 / 100
3-month rank in its sector · Healthcare466 / 720

Chart structure

Read by our daily-bar structure engine from swing highs, swing lows and moving averages.

Intermediate downtrend · DeclineConfirmed

Holding since Oct 7, 2026

  • Close below EMA20 below EMA50
  • EMA50 fell over the last ten sessions
  • Some swings conflict with the averages
This pattern on this stock

90 occurrences in 10 years. The median move over the next 20 sessions was +2.0%, positive 60% of the time, against +0.6% for any day in the same period.

Reference zone, stop and targets for this structureSee the trade plan in Hub ↗

Analyst earnings revisions

Changes to the consensus forward-EPS estimate. Rising estimates mean analysts see more profit ahead.

Forward EPS$12.48
30-day change0.0%
90-day change−6.9%
Mean target$369.66 +64.2%
Raised (30d) 0Cut (30d) 2

26 analysts cover the stock

Fundamental shape vs peers

Six dimensions on fixed scales. The filled shape is the company; the outline is the peer average.

Open the full Radar with every ratio
ValuationRevisionsMomentumGrowthCashProfit

Ahead of peersGrowth, Profit

Behind peersMomentum, Revisions

PeersVRTX · MRNA · REGN · ARGX

Where it sits in the supply chain

Healthcare Value Chain · Drugs & devices

Explore the full chain map in Hub
Supplied by
Life-science tools & bioprocessing+6.0%
TMO+5.4%1 monthDHR+6.0%1 monthA+6.4%1 month
Clinical research outsourcing+8.0%
IQV+2.4%1 monthFTRE+17.8%1 monthICLR+10.9%1 monthMEDP+5.1%1 month
Its segment
Biotech+0.4%
AMGN+6.8%1 monthREGN+0.2%1 monthGILD+0.6%1 monthVRTX+1.9%1 monthALNY−10.6%1 monthMRNA+34.6%1 monthBIIB+6.9%1 monthINSM−22.2%1 monthINCY−10.6%1 monthCATX−22.3%1 month

Built on a few major drugs or platforms, with shares highly sensitive to trial data and regulatory decisions.

Sells into
Drug distribution+13.9%
MCK+13.9%1 monthCOR+8.3%1 monthCAH+16.2%1 month

Figures are each company's 1-month return; the segment shows its median · Doubler daily batch · company chain maps

Risk profile

Max drawdown, 12M−57.3%
Volatility, 60D74.2%
From 52-week high−53.3%
From 52-week low+9.5%
Trailing P/E39.2×
Forward P/E18.0×

Themes

  • Biotech Platform3M rank 217 / 414
AMGNAmgenREGNRegeneron PharmaceuticalsGILDGilead SciencesVRTXVertex PharmaceuticalsMRNAModerna, Inc.BIIBBiogen Inc.INSMInsmed IncorporatedINCYIncyte Corporation

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